Genomics of the innate immune system

SR-Tiget Unit
Renato Ostuni, SR-Tiget Group Leader


Our Group uses a multidisciplinary approach, integrating high-throughput/low-input and single-cell genomics, genome engineering and bioinformatics to dissect the epigenomic principles of myeloid cell functions in vivo. Using highly relevant in vitro and in vivo models in the mouse as well as uniquely available clinical samples, we aim to decipher the complex networks of signaling pathways, transcription factors (TF), chromatin regulators and non-coding RNA that converge on transcriptional enhancers and promoters to control gene expression in the innate immune system.
The lab is always looking for enthusiastic and highly motivated scientists at all levels of training. Wet and computational scientists aiming to tackle fundamental questions of direct clinical relevance using highly advanced experimental tools are encouraged to send an e-mail to: ostuni.renato@hsr.it.

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