Anna Villa

Gene therapy for WASP/Omenn

SR-Tiget Unit
Anna Villa, Head of Unit

villa.anna@hsr.it



The main goal of our Unit is to investigate the mechanisms underlying autoimmune manifestations occurring in two syndromes, Wiskott-Aldrich syndrome and Omenn Syndrome, characterized by severe infections associated with immune dysregulation. To this end, we will take advantage of mouse models that well recapitulate the clinical phenotype of the diseases. In parallel, we are studying the efficacy of gene therapy in correcting the defective phenotypes revealed in our analysis.

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