Human hematopoietic development and disease modeling unit

SR-Tiget Unit
Andrea Ditadi, SR-Tiget Group Leader


The Ditadi lab is a young and dynamic group whose focus is to understand and recapitulate normal and pathological human hematopoietic development, at the signaling and genetic level, with the goal of generating blood cell products, to be used in the regenerative medicine framework. Most of the studies harness the potential of human pluripotent stem cells (hPSC; comprising human embryonic stem cells - hESC - and induced pluripotent stem cells - hiPSC). The ability to generate functional blood cells from hPSCs in culture would represent an important step forward, as it would provide an unlimited source of these cells for therapeutic applications as well as a model for studying human hematopoietic development and disease in vitro.

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