Age related diseases

Simone Cenci, Group Leader


Our research is mainly focused on the basic cell biology of normal and malignant plasma cells, with implications for Ab responses and Multiple Myeloma (2% of all cancer deaths). The overall goal is to understand how plasma cells cope with proteotoxic stress to identify novel targets against plasma cell cancers. A strong background in bone cell biology and in vivo mouse studies, along with ongoing investigations on differentiation of osteoclasts, unique bone-resorbing cells, provides expertise and models to extend our studies to the myeloma bone marrow milieu.

Curriculum vitae


2000 Specialization in Gerontology and Geriatrics, University of Perugia, Italy
1995 MD Degree, University of Perugia, Italy

Professional experiences

2006-today Staff Scientist, San Raffaele Scientific Institute, Milan, Italy
2003-2006 Junior Researcher, San Raffaele Scientific Institute, Milan, Italy
1998-2003 Research Associate, Division of Bone and Mineral Diseases, Internal Medicine, Washington University in St. Louis, MO, USA, studying the role of immune cells in post-menopausal osteoporosis


2009 Career Establishment Award, European Calcified Tissue Society
1998 and 2000 Young Investigator Award, American Society for Bone and Mineral Research


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