Cenci profilo

Age related diseases

Simone Cenci, Head of Unit


Our lab studies the biology of normal plasma cells (PC), terminally differentiated effectors of antibody responses, and their malignant counterpart, multiple myeloma (2% of all cancer deaths). We are interested in the role of autophagy in PC ontogenesis and myeloma, in search for new molecular targets and markers of clinical use against PC cancers. Synergic studies on the skeletal microenvironment and bone cells explore the vicious relationship of myeloma with the bone marrow.